Thursday
Sep022010
Thu, September 2, 2010 Lead Exposure, Parent's Smoking Alters Puberty In Girls
A new study funded by the National Institute of Child Health and Human Development, or NICHD, finds that childhood exposure to lead can suppress the hormones young girls need to develop properly. And when that exposure is married to exposure to cadmium—from cigarette smoke, for example—the effect is even more pronounced.How serious is this? Well this research found that girls who had elevated levels of those metals in their systems were up to 75% less likely to make those very important sex hormones than girls with more normal levels of those pollutants in their blood.
The scientists behind this study admit they don’t have all the answers but they theorize that the lead and cadmium work directly on the girls’ ovaries. By suppressing the ovaries’ natural functions, these metals also suppress the hormones the ovaries need to begin ovulation.
So where does cigarette smoke come in? While there’s not a lot of research specifically on cadmium from second-hand smoke, cigarettes are considered a leading exposure risk for this toxin; in fact, a 1998 study found that 50% of the cadmium intake of a typical smoker came from his or her own cigarettes. And as much as 60% of the cadmium inhaled in cigarette smoke will be absorbed by the body—where it can accumulate in the kidneys for as long as 30 years.
This information came from data collected as part of the Third National Health and Nutrition Examination Survey. The actual study appears in July’s issue of Environmental Health Perspectives.
Sources:
Gollenberg, A., et al. (2010). Association Between Lead and Cadmium and Reproductive Hormones in Peripubertal U.S. Girls. Environmental Health Perspectives.
Van Assche, F., et al. (1998). Cadmium in the Environment: Levels, Trends and Critical Pathways. Presented at the Seventh International Cadmium Conference.

